Apical incisor root resorption due to ectopic maxillary canine eruption: Association with time of diagnosis and type of intervention in a retrospective population-based cohort study.

OBJECTIVES: The primary aim was to study upper incisor severe apical root resorption (RR) related to ectopic canine eruption and its association with timing of diagnosis and type of intervention conducted. The secondary aim was to correlate resorption with other dental anomalies. MATERIALS AND METHODS: Digital journals and radiographic material of all ectopic maxillary canines registered in 2012 in the regional public paediatric dental clinics in the Council of Aarhus were inspected retrospectively. Data related to 10 variables were retrieved. Post-treatment radiographs were used for evaluation of incisor RR. RESULTS: A total of 260 ectopic maxillary canines were diagnosed in 2012. The majority were found in the 9-13-year-old age group (0.8% prevalence within the total population). In all, 244 canines were assessed for eligibility and 181 had adequate final radiographs for evaluation of RR. Among ectopic maxillary canines, 9.4% caused severe incisor RR to neighbouring teeth. Timely palpation for canine eruption significantly reduced the odds for upper incisor resorption by 80%. Multiple regression showed that when the permanent canine cannot be palpated and the deciduous has been extracted, delaying the first X-rays was associated with a 38% odds ratio increase for RR for each year of delay after the age of 10 years. No significant associations were found between incisor RR and intervention conducted or other dental anomalies. CONCLUSION: Palpation of erupting maxillary canines is crucial for timely diagnosis of ectopic eruption and initiation of treatment to avoid RR. If the canine cannot be palpated at 10 years of age, radiographic examination is highly recommendable.

Redirection of palatally ectopic maxillary canines: Case report and proposition of an interceptive sequential guideline.

The eruptive deviation of the permanent maxillary canine must be identified early, at the beginning of the second transitional period of the mixed dentition. Acting at this moment is fundamental for its spontaneous redirection and eruption. The aim of the paper is to present a case where the extraction of the deciduous canines was the choice for redirecting the maxillary permanent canines with eruptive palatal deviation, as well as to suggest a sequence of procedures for diagnosis and choice of treatment. The success of deciduous canine extraction in redirecting the ectopic permanent canines is discussed in this case, as well as aspects that might lead to failure. Still, it highlights the importance of computed tomography for choosing conservative treatment or traction, including it in the sequential guideline for acting in these cases.

Management Of Ectopic Eruption Of Bilateral Mandibular First Permanent Molars: A Case Report And Literature Review.

Ectopic eruption of the first permanent molars is a local eruption disturbance. The frequency of ectopically erupted first permanent molars is predominant in boys and primarily affects the maxilla. Interceptive treatment for irreversible ectopic eruptions should be initiated early to prevent space loss and the impaction of the second premolars. Herein, we report the case of a six-year-old girl with irreversible ectopic eruption of the bilateral mandibular first permanent molarstreated with a modified lingual arch. The mandibular first permanent molars were successfully distalised after six months of treatment, and one year of follow-up showed a satisfactory outcome. The modified lingual arch satisfies not only the clinical aspects of treatment but also the patient's well-being. However, the lingual arch may disturb tooth eruption in the mixed dentition stage.

[Diagnosis and orthodontic treatment strategy of complete canine transposition].

Tooth transposition is a challenge for orthodontists, especially in correcting the order of teeth. At present, the literature on transposition canines mainly focuses on epidemiological studies and case reports, and no systematic treatment guidance has been formed. In this article, the definition and classification, epidemiology and etiology, imaging diagnosis, treatment and risk control of transposed canines are systematically described in order to provide reference for clinical practice.

Do the various interceptive treatment modalities improve the position of palatally displaced permanent canines? A meta-analysis.

BACKGROUND: Removal of maxillary primary canines and other interceptive treatment modalities in the mixed dentition have been suggested as methods used to increase the rate of normal eruption of palatally displaced permanent canines (PDCs). However, the information on the overall effect on PDCs' position has been inconclusive. OBJECTIVE: To assess whether this practice improves the position of PDCs and to investigate the quality of the evidence. SEARCH METHODS: Unrestricted searches in 7 databases and manual searching of the reference lists in relevant studies were performed up to June 2022 (Medline via PubMed, CENTRAL, Cochrane Database of Systematic Reviews, Scopus, Web of Science, ClinicalTrials.gov, ProQuest Dissertations, and Theses Global). SELECTION CRITERIA: We looked for data on the positional changes of PDCs (mesial inclination, vertical position, canine crown cusp tip to midline) from randomized controlled trials assessing the various interceptive treatment modalities. DATA COLLECTION AND ANALYSIS: Following study retrieval and selection, relevant data were extracted, and the risk of bias was assessed using the Cochrane Risk of Bias 2 Tool. Exploratory synthesis and meta-regression were conducted using the random effects model and the overall quality of the available evidence was assessed with the Grades of Recommendation, Assessment, Development, and Evaluation approach. RESULTS: Five studies (3 at low risk of bias) were identified, involving 238 individuals, followed for up to 18 months post-intervention with OPG (orthopantomogram) or CBCT (cone-beam computed tomography). Exploratory data synthesis showed that PDCs' position improved more in the extraction sites compared to non-extraction. Analysis of the studies at low risk confirmed the above observations (6- and 12-month). Improvements were observed in patients using headgear after extraction of primary canines compared to extraction alone, but not in patients with double extraction of primary canines and first molars. The quality of available evidence was rated at best as moderate. CONCLUSIONS: Interceptive treatment modalities in the mixed dentition may improve the position of PDCs. However, more studies are necessary in order to determine the clinical significance of the changes. REGISTRATION: PROSPERO (CRD42015029130).

Evaluation of the position of the permanent maxillary canine and its relationship to dental anomaly patterns in the paediatric patient.

AIM: To evaluate the prevalence of ectopic eruption of the permanent maxillary canine in patients 6 to 10 years of age and its relationship to other dental anomalies, age and sex of the patient. MATERIALS: Study design: Descriptive, cross-sectional, observational, and retrospective study METHODS: A total of 260 panoramic radiographs were collected from patients who had their first visit at the Paediatric Dentistry Department of the Hospital HM Nens, HM Hospitals in Barcelona from January to May 2021. The prevalence of ectopic eruption was evaluated based on the following variables: age, sex, inclination angle and mesiodistal position of the crown of the permanent maxillary canine. Additionally, the presence of other dental anomalies was recorded. The statistical analysis to evaluate the relationship between two categorical variables was carried out using the Chi-square (or Fisher) test with unrelated samples and the Mann-Whitney test with related samples. A p-value of 0.05 and a 95% reliability level were considered statistically significant. CONCLUSION: The prevalence of ectopic eruption of the permanent maxillary canine was 9.23%. In this sample, no relationship was found between patients with maxillary canine with abnormal position and inclination and the presence of other dental anomalies.

Artificial intelligence-aided detection of ectopic eruption of maxillary first molars based on panoramic radiographs.

OBJECTIVES: Ectopic eruption (EE) of maxillary permanent first molars (PFMs) is among the most frequent ectopic eruption, which leads to premature loss of adjacent primary second molars, impaction of premolars and a decrease in dental arch length. Apart from oral manifestations such asdelayed eruption of PFMs and discoloration of primary second molars, panoramic radiographs can reveal EE of maxillary PFMs as well. Identifying eruption anomalies in radiographs can be strongly experience-dependent, leading us to develop here an automatic model that can aid dentists in this task and allow timelier interventions. METHODS: Panoramic X-ray images from 1480 patients aged 4-9 years old were used to train an auto-screening model. Another 100 panoramic images were used to validate and test the model. RESULTS: The positive and negative predictive values of this auto-screening system were 0.86 and 0.88, respectively, with a specificity of 0.90 and a sensitivity of 0.86. Using the model to aid dentists in detecting EE on the 100 panoramic images led to higher sensitivity and specificity than when three experienced pediatric dentists detected EE manually. CONCLUSIONS: Deep learning-based automatic screening system is useful and promising in the detection EE of maxillary PFMs with relatively high specificity. However, deep learning is not completely accurate in the detection of EE. To minimize the effect of possible false negative diagnosis, regular follow-ups and re-evaluation are required if necessary. CLINICAL SIGNIFICANCE: Identification of EE through a semi-automatic screening model can improve the efficacy and accuracy of clinical diagnosis compared to human experts alone. This method may allow earlier detection and timelier intervention and management.

An assessment of root stage of canine and premolar teeth at alveolar eruption.

OBJECTIVE: The primary aim was to evaluate the degree of root development of permanent canines at the time of alveolar eruption. We also aimed to assess whether differences in the degree of root development at alveolar eruption exist between permanent canines and premolars and between maxilla and mandible. DESIGN: A cross-sectional study. SETTING: Barts and The London School of Medicine and Dentistry, Queen Mary University of London. PARTICIPANTS: Two hundred dental panoramic radiographs taken as part of routine dental care. METHODS: Radiographs were assessed for canine and premolar root development stage and eruption level with calibration and repeat measurements undertaken. RESULTS: Two hundred and sixty teeth were identified as being at the level of alveolar eruption. The majority of maxillary canines reached alveolar eruption when root formation was complete. Most premolars and mandibular canines reached alveolar eruption when roots were three-quarters developed. At alveolar eruption, canines were statistically more mature than premolars (p<0.001) and maxillary teeth were more mature than mandibular teeth (p<0.05). CONCLUSIONS: Root development appears to be particularly advanced for maxillary permanent canines, being essentially root-complete at alveolar eruption, while premolars and mandibular permanent canines appear to have three-quarters root development at this stage. This information may be used to inform whether and when to extract primary teeth for orthodontic reasons.

Rapid maxillary expansion for interceptive orthodontic treatment of palatally displaced canine: A systematic review.

AIM: The present systematic review aims to summarise the relevant randomised clinical trials and estimate the efficacy of interceptive orthodontic intervention, in particular if an interceptive treatment with rapid maxillary expansion could be successful in managing of palatally displaced canines (PDCs). MATERIALS AND METHODS: A search strategy was developed on electronic databases including Medline, Web of Science, Scopus and Cochrane Collaboration Trial from 1925 to 2019. Two reviewers independently reviewed the sources deciding for a full reading according to the inclusion and exclusion criteria. Methodological quality criteria were applied to the selected articles. RESULTS: Three randomised clinical trials (RCTs) and one prospective longitudinal study were included in the systematic review. Generally, the intervention groups showed a higher incidence of successful eruption of PDCs (45.1% - 65.7%) compared with the control groups (13.1% - 13.6%). CONCLUSIONS: Based on the literature published, authors reached a reasonable conclusion that rapid maxillary expansion can facilitate the eruption of PDCs. Authors suggest to associate maxillary expansion with deciduous canine extraction or prevention of mesial movement of the upper first molars.

Dental age estimation of young subjects with unilateral palatally displaced canine teeth.

INTRODUCTION: Delayed tooth eruption is often seen in patients with palatally displaced canines (PDC), but there is controversy over whether tooth formation is also delayed. This study attempts to elucidate the answer by addressing methodological shortcomings in previous studies. METHODS: Archived records were searched, and 100 patients (aged 8-16 years) with unilateral PDC were identified. Records of 50 women and 50 men were matched for age and sex with unaffected controls. The exclusion criteria included hypodontia. Dental age (DA) was calculated using the population-specific Maltese database and subtracted from the chronological age (CA). Nonparametric tests were used to compare CA-DA in patients with PDC and controls to determine the DA of end-of-series teeth. RESULTS: No statistically significant difference with CA-DA between patients with PDC and controls was found. In addition, there were no particular teeth significantly delayed in development. CONCLUSIONS: Unilateral PDC does not affect dental developmental age, and the end-of-series teeth investigated show no delay in development.

Two-phase orthodontic treatment of two different types of tooth transposition in the same patient.

Orthodontic treatment is thoroughly planned considering the patient's facial and dental characteristics, the main complaint, treatment time and the orthodontist's experience. Transposition is a form of ectopia, in which two adjacent teeth exchange positions in the dental arch. Transposition can be partial or complete. This article reports the treatment of a female patient with two kinds of tooth transposition managed in the mixed and permanent dentitions. A girl, aged eight years and three months, came to routine paediatric consultation with an ectopic permanent mandibular left lateral incisor in the mixed dentition. Radiographic analysis indicated partial transposition of the permanent mandibular left lateral incisor and canine (Md.L2.C), and development of a complete tooth transposition between the permanent maxillary right first pre-molar and canine (Mx.C.P1). The patient was treated in two phases. The first, in the mixed dentition, and the second, in the permanent dentition with a three-year follow-up between them. These challenging treatment approaches are described in detail, including the mechanics used. The key points of this treatment were early diagnosis of the ectopic mandibular lateral incisor, use of light forces and interphase patient follow-up. These determined the best time to start the second treatment phase, enabling achievement of aesthetic and functional outcomes, and the results remained stable one year after the end of orthodontic treatment.

Mandibular lateral incisor-canine transposition: A case series.

Dental transpositions are rare anomalies, which may present to the general dental practitioner or orthodontist. Transpositions occur less frequently in the mandible compared with the maxilla, with the most common mandibular transposition involving the mandibular lateral incisor and canine. The degree of displacement can vary from a relatively minor deviation to complete transposition of the mandibular lateral incisor with the adjacent canine tooth. Due to their highly visible position at the front of the mouth, treatment, ideally involving alignment of these teeth, is important for aesthetic, social and functional purposes. This case series reports six cases with mandibular lateral incisor-canine transposition. They demonstrate the variety in presentation and subsequent management of the ectopic teeth. The importance of early diagnosis in combination with interceptive treatment is discussed, to reduce the burden of potentially lengthy orthodontic treatment at a later date.

Ectopic eruption of the first permanent molar: Predictive factors for irreversible outcome.

INTRODUCTION: The present study aimed to analyze possible factors involved in irreversible (IRR) ectopic eruption (EE) of the first permanent molar and explore potential predictors for the IRR outcome. METHODS: Children aged 4-11 years, with at least 1 EE and who took their first panoramic radiograph before the age of 8 years, were selected in this study. The subjects were assigned to the self-correcting (SC) and IRR groups. Patients' age, sex, distribution of EE, and accompanying dental anomalies were recorded. Eruptive angulation (EA) of the first permanent molar, the grade of root resorption in the second deciduous molar, the magnitude of impaction index (MOII), and horizontal distance were measured on the panoramic radiographs. Chi-square tests and independent-sample t test were used for nominal and continuous variables, respectively. The receiver operative characteristic curve was used to determine the critical value. RESULTS: A total of 406 children with 634 first permanent molars, presenting EE, were enrolled, with 61.3% of the teeth in the SC group. Sex of children with EE and distribution of EE were not relevant to the IRR outcome. The presence of supernumerary teeth might be a protective factor for the IRR outcome. The increasing severity of root resorption in the second primary molar indicated an IRR outcome. A higher MOII and a larger EA suggested an IRR outcome with moderate-to-high quality. The horizontal distance exhibited debatable results, with a low predictive quality. CONCLUSION: Close monitoring and early intervention would benefit children with increasing severity of distal atypical resorption in the second primary molar, higher MOII, and larger EA.

Management of ectopically erupting permanent molars in a seven-year-old girl: A case report.

Ectopic eruption of permanent first molar is a developmental disturbance, leading to many local problems, such as premature loss of the second primary molars, space loss, increased prevalence of dental caries, supraeruption of the opposing molars, mesial inclination of the permanent maxillary first molars and class II molar relationship. We report the case of a seven-and-a-half-year-old girl with ectopic eruption of permanent maxillary and mandibular first molar, treated by orthodontic separators and slicing the distal surface of the adjacent primary second molar separately. Regular examination and timely interception are important during oral health management of children and is of great significance in alleviating the side effects of ectopic eruption.

Frequency and association of maxillary ectopic canine with incisor root resorption and dental agenesis.

OBJECTIVE: To assess the frequency of maxillary ectopic canine both buccally and palatally displaced with incisor root resorption and dental agenesis. METHODS: The cross-sectional study was conducted from April 8 to June 29, 2019, at the Department of Orthodontics, Dr. Ishrat Ul Ebad Khan Institute of Oral Health Sciences, and Dow Dental College, Dow University Of Health Sciences, Karachi, and comprised orthodontic patients diagnosed with maxillary ectopic canine eruption. Root resorption and agenesis were diagnosed on panoramic films. Root resorption was further confirmed by periapical radiographs. Data was analysed using SPSS 21. RESULTS: Of the 98 subjects, 86(87.8%) had buccally displaced canines of which 38(44.2%) were associated with root resorption, while 12(12.2%) patients had palatally displaced canines of which 10(83.3%) had root resorption (p=0.011). Overall, 30(30.6%) lateral incisors were resorbed, 7(7.1%) both central and lateral incisors, 5(5.1%) premolars, and 6(6.1%) both lateral incisors and premolars were resorbed. Agenesis was detected in 10 (10.2%) subjects (p=0.62). CONCLUSIONS: There was found to be no association of maxillary ectopic canines with incisor root resorption and dental agenesis.

Ectopic eruption of maxillary permanent first molars: Predictive factors for self-corrected and impacted outcome.

OBJECTIVE: The aim of this study was to describe the occurrence, angulation and mesialisation ratio of the ectopic eruption of the maxillary permanent first molar (PFM) and its correlation with the pathological resorption of maxillary primary second molar (PSM). METHODS: This retrospective study was performed using the subsequent panoramic radiographs of 11.924 child patients aged 6-10 years. Ectopic eruption status is categorised as self-corrected and impacted types. To evaluate the differences between the two groups (self-corrected and impacted), the angulation of PFM, mesialisation ratio of PFM, and degree of adjacent PSM root resorption were also assessed. The data were statistically analysed using ANOVA and chi-square tests. Pearson correlation was used to analyse whether a quantitative relationship exists between PFM mesialisation ratio and PSM root resorption. RESULTS: Ectopic eruption frequency was determined as 0.83%. The distribution of ectopic eruption according to gender shows a higher prevalence in males than females. In most cases of ectopic eruption, the eruption status was impacted. The impacted PFMs showed more negative vertical and positive horizontal angle between the PSM and PFM. There was no significant difference between eruption status and angles. Mesialisation ratio of impacted PFMs was significantly higher than self-corrected PFMs. There was significant difference between the PFM mesialisation ratio and the degree of PSM root resorption. CONCLUSION: Even if eruption disturbances do not occur frequently, making an early diagnosis is important to begin treatment at an optimal time. Although the relationship between horizontal and vertical angles and the ectopic eruption pattern is controversial, it is one of the clinical determinants. The mesialisation ratio of the impacted type was significantly higher than the self-corrected type. Self-correction of PFM was reduced in PSM with grade III and IV root resorption.

Orthodontic management of a complete and an incomplete maxillary canine-first premolar transposition.

Maxillary canine and first premolar transposition is a complicated dental anomaly to treat, especially if the clinician's goal is to orthodontically move the canine into its normal position. Early diagnosis with cone-beam computed tomography simplifies the treatment of this pathology. This case report describes a patient with bilateral transposition, one complete and the other incomplete, involving the maxillary canine and the first premolar (Mx.C.1P). The orthodontic treatment involved the correction of both transpositions. In the complete transposition, the traction was mesial and upward to move the canine into a more apical position with a wider dentoalveolar process for easier crown interchange.

Double vs single primary tooth extraction in interceptive treatment of palatally displaced canines.

OBJECTIVES: To compare the impact of primary canine and primary first molar extractions with extractions of only the primary canine regarding correction of palatally displaced canines (PDCs). MATERIALS AND METHODS: Thirty-two children aged 9.5-13.5 years with 48 PDCs were randomly allocated to either the double-extraction group (DEG) or single-extraction group (SEG). Clinical and radiographic examinations were performed at baseline and at 6-month intervals until the canine emerged or orthodontic treatment was started. Outcome measures were: emergence of maxillary canine (yes/no), emergence of maxillary canine into a favorable position (yes/no), and maxillary canine positional change (angulation and sector). Factors influencing PDC emergence were analyzed using logistic regression. RESULTS: In the DEG, 64% (16/25) of canines emerged into the oral cavity vs 78% (18/23) in the SEG (P = .283). Favorable PDC position at trial end was seen in 64% (16/25) of the DEG vs 57% (13/23) of the SEG (P = .600). Significant distal movement of PDCs was recorded in the DEG and SEG, though no significant difference was observed between groups. Significant predictors of canine emergence were initial canine angulation (Angle A) (P = .008) and space conditions at T0 (P = .030). CONCLUSIONS: Double or single primary tooth extraction procedures are equivalent in supporting PDC eruption into the oral cavity and into a favorable position in the dental arch. Initial canine angulation and space assessments may be used as predictors of successful PDC eruption.